How to make rune words in Diablo 2: Resurrected - IGMeet Diablo 2: Resurrected Guide Runewords are combinations of Runes slotted into specific weapons in a particular order. It sounds complicated because, well, it is. There’s a lot to take into account when crafting Runewords, and you will need to learn all of that before you can start crafting them yourself. They’re worth the effort, though; Runewords and D2R Ladder Items are upgrades you apply to your...